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MAYSVILLE, Mo. — DeKalb County Sheriff Andy Clark was killed Wednesday in a crash while responding to assist a deputy, according to the Buchanan County, Missouri Sheriff’s Office.

According to the Missouri State Highway Patrol, Clark was southbound in a Chevy pickup on Missouri, crossing over to eastbound U.S. 36 when the driver of a GMC SUV on U.S. 36 struck the passenger side of Clark’s vehicle.

Clark was pronounced dead at the scene. He was 43-years-old. He was not wearing a seatbelt, according to the highway patrol.

The 71-year-old driver of the SUV and three occupants were taken to the hospital with minor to moderate injuries. The driver was reported to be wearing a seatbelt.

“The men and women of the sheriff’s office want to extend our deepest heartfelt condolences to Sheriff Andy Clark’s family, and the brave men and women of the DeKalb County Sheriff’s Office, the department posted on Facebook Monday afternoon. “Please keep Sheriff Clark’s family and the DeKalb County Sheriff’s Office in your thoughts and prayers.”

Multiple other law enforcement agencies across Kansas and Missouri have shared the condolences.

“We mourn the loss of Sheriff Andy Clark of the Dekalb County Missouri Sheriff’s Office. Please keep his family, both blood and blue, in your prayers,” the Atchison Kansas Police Department said.

“We offer our heartfelt condolences to Sheriff Clark’s family at home and at his office, and to all DeKalb County Communities,” Audrain County Sheriff’s Office said.

The Lewis County Sheriff’s Office released a statement saying “Everyone at our office, and our families, offer our heartfelt condolences to Sheriff Clark’s family, to everyone at his office and to the DeKalb County community.”

“The Men and Women of the McDonald County Sheriff’s Office want to extend our deepest heartfelt condolences to Sheriff Andy Clark’s family, and the brave men and women of the DeKalb County Sheriff’s Office,” the department said. “Please keep Sheriff Clark’s family and the DeKalb County Sheriff’s Office in your thoughts and prayers”

The cause of the crash is under investigation.

This is a developing story. FOX4 will continue to keep you updated as details become available.